What thread sizes is Loctite 221 suitable for?

This threadlocker is designed for small threaded fasteners up to a maximum size of M12.

Can fasteners secured with Loctite 221 be disassembled?

Yes, its low strength allows easy disassembly using standard hand tools.

What is the benefit of the low viscosity?

The liquid consistency flows easily into tight tolerances and fine threads.

Which metals are compatible with Loctite 221?

It is suitable for metal threaded fasteners, including steel, stainless steel, and brass.

What is the volume of this bottle?

This bottle contains 250 ml of liquid threadlocker.

LOCTITE 221 low-strength, low-viscosity threadlocker (250 ml bottle) - 142444

Name: LOCTITE 221 low-strength, low-viscosity threadlocker (250 ml bottle) - 142444
Brand: LOCTITE
SKU: 02147947
Price: 246.95 EUR
Availability: InStock

Supplier number: LOCTITE 142444 | EAN 5010266169675

Recommended Retail Price €312.23

246.95 tax incl.

€204.09 excl. VAT (incl. all environmental contributions)

On stock - immediately available | we have 1 products in stock.

Ordered before 20:00 - delivered as of 05/10/2026
Free shipping
Delivery by DHL

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How does it work?

For a purchase value of €99 to €125 excl. VAT, receive FREE LOCTITE 55 thread sealing cord 50 m (IDH 528244) worth €9.99.
For a purchase value of more than €125 excl. VAT, receive FREE LOCTITE SF 7850 hand cleaner 400 ml (IDH 2098250) worth €13.21.
The free item is automatically added to your order. No registration is required.
The promotion is valid from 01.10.2026 to 31.10.2026.
Loctite Buy & Get deals are recognisable by the promotion label on the product page. Click the label to view all available deals.

Secure locking with Loctite 221

Practical benefits

Easy disassembly with hand tools: You remove low-strength fastened bolts smoothly using standard hand tools without shearing the threads.
Ideal for small threads: The low viscosity allows the formula to penetrate easily into fine threads up to M12.
Resistance against vibration loosening: You prevent fasteners from backing out or leaking when exposed to continuous shock and movement.

In a nutshell

The right choise for

With Loctite 221, you securely lock small threaded fasteners up to M12 against loosening caused by shock and vibration. Thanks to its low viscosity, this liquid threadlocker easily flows into tight tolerances and fine threads on steel, stainless steel, and brass. Because of its low strength, you can disassemble set screws and components smoothly using standard hand tools without stripping threads or damaging fastener heads. Supplied in a generous 250 ml bottle, it is ideal for demanding tasks in precision mechanics, electronics, and instrumentation.

Product information FAQ

€246.95

In stock - tax incl.

Key features according to our expert

Net volume: 250 ml
P-statements: P101; P102; P261; P273; P337 + P313; P501
ADR packing group: Not applicable
ADR class: Not applicable
UN number: Not applicable
Principal hazard property: GHS07 Harmful or irritant
H-statements: H319; H335; H412
Hazard class: GHS07 Harmful or irritant
Physical state: Liquid
Flash point: > 100 °C
Max. thread size: Up to M12
Strength (locking compound): Low

Product description:

LOCTITE 221 is a methacrylate-based threadlocking adhesive designed for low strength applications on small threads up to a maximum size of M12.
Typical fixture times are 25, 20 and 210 min on steel, brass and stainless steel respectively.
Offering low viscosity and a breakaway torque of 8.5 Nm, the product is designed for fasteners that require easy disassembly with standard hand tool

Precautionary statements

P101: If medical advice is needed, have product container or label at hand.
P102: Keep out of reach of children.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P273: Avoid release to the environment.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P501: Dispose of contents/container to ... (see safety data sheet).

Hazard statements

H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H412: Harmful to aquatic life with long lasting effects.

All Features

Net volume: 250 ml
P-statements: P101; P102; P261; P273; P337 + P313; P501
Adr packing group: Not applicable
Adr class: Not applicable
Un number: Not applicable
Principal hazard property: GHS07 Harmful or irritant
H-statements: H319; H335; H412
Hazard class: GHS07 Harmful or irritant
Physical state: Liquid
Flash point: > 100 °C
Max. thread size: Up to M12
Strength (locking compound): Low

Brand LOCTITE
02147947
EAN 5010266169675
Supplier number LOCTITE 142444

Frequently asked questions about this product

Answered by specialists

What thread sizes is Loctite 221 suitable for?: This threadlocker is designed for small threaded fasteners up to a maximum size of M12.
Can fasteners secured with Loctite 221 be disassembled?: Yes, its low strength allows easy disassembly using standard hand tools.
What is the benefit of the low viscosity?: The liquid consistency flows easily into tight tolerances and fine threads.
Which metals are compatible with Loctite 221?: It is suitable for metal threaded fasteners, including steel, stainless steel, and brass.
What is the volume of this bottle?: This bottle contains 250 ml of liquid threadlocker.